PROFIL PRACOWNIKA: Rafał Głowacki
prof. dr hab. Rafał Głowacki
SCIENTIFIC AND SOCIAL MEDIA PROFILES
POSITION DESCRIPTION
1. The Dean manages the faculty and is its representative.
2. The Dean is the superior of the employees and students who are part of the faculty, based on the authorization of the Rector.
3. The Dean makes decisions regarding the functioning of the faculty, which do not fall within the competence of the University bodies.
4. In particular, the Dean:
1) makes decisions on behalf of the Rector within the framework of the power of attorney granted by the Rector;
2) develops a development strategy for the faculty in accordance with the development strategy of the University;
3) manages the financial management of the faculty;
4) submits a draft of the faculty's material and financial plan to the faculty council;
5) on the basis and within the limits of the power of attorney granted by the Rector, incurs liabilities and makes expenditures on behalf of the University in the scope concerning the faculty, and also performs other legal acts concerning the University's property at the disposal of the faculty, with the exception of the sale and encumbrance of real estate;
6) coordinates teaching activities at the faculty;
7) undertakes activities in the field of research activities resulting from decisions of the board of science;
8) makes decisions or submits motions regarding the appointment and dismissal of heads of organizational units of the faculty;
9) makes decisions and submits motions in other matters related to the activities of the faculty.
The head of the department:
1) represents the department externally;
2) supports the development of research projects;
3) supports research in the disciplines covered by the department's activities;
4) organizes and supervises the teaching activities of the department;
5) submits applications to the faculty council or the dean, including applications concerning employment, other employee matters and awards for department employees;
6) manages the department's property and allocated financial resources, subject to separate regulations;
7) submits annual reports on the department's activities to the dean.
Duties include:
1. conducting research,
2. conducting classes,
3. applying for research funds,
4. substantive supervision of PhD students,
5. activities related to managing the Department of Environmental Chemistry.
INTERESTS
1. Analysis of biological samples and chemical analysis of environmental pollutants using separation techniques, including:
high-performance liquid chromatography (HPLC-MS/MS; HPLC-UV-Vis DAD; HPLC-FLD; HPLC-LSD), gas chromatography (GC-MS), capillary electrophoresis (CE-UV-Vis DAD).
2. Chemistry and biochemistry of thiol amino acids, homocysteine thiolactone and their metabolites.
3. Development of analytical methods enabling the determination of selected biologically important compounds in complex matrices.
4. Preparation of a biological sample for analysis; chemical derivatization.
5. Study of the possibilities of increasing sensitivity in capillary electrophoresis using concentration of analytes in the capillary.
ACHIEVEMENTS
Some publications:
1. A. Undas, J. Perła‑Kaján, R. Głowacki, Homocysteine in adult patients with cardiovascular disease: is it clinically relevant in 2025? A tribute to Hieronim Jakubowski, (1946–2025), Polish Archives of Internal Medicine, 135 ( 2025) 1-8.
2. A. Krata, J. Domagała, R. Głowacki, Hydrophilic interaction liquid chromatography based method for simultaneous determination of purines and their derivatives in food spices, Food Chemistry, 441 (2024) 138285.
3. J. Piechocka, R. Głowacki, Comprehensive studies on the development of HPLC-MS/MS and HPLC-FL based methods for routine determination of homocysteine thiolactone in human urine, Talanta, 272 (2024) 125791.
4. J. Piechocka, N. Matwiej, M. Gaweł, M. Matyjaszczyk, R. Głowacki, G. Chwatko, Application of the HPLC-ELSD technique for the determination of major metabolites of ibuprofen and creatinine in human urine, Scientific Reports, 13 (2023) 20268.
5. J. Piechocka, R. Głowacki, One-pot sample preparation procedure for the determination of protein N-linked homocysteine by HPLC-FLD based method, J. Chromatogr. B, 1228 (2023) 123835.
6. J. Piechocka, M. Wyszczelska-Rokiel, R. Głowacki, Simultaneous determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid and main plasma aminothiols by HPLC-UV based method, Scientific Reports, 13 (2023) 9294, 1-12.
7. J. Piechocka, R. Głowacki, Up-to-date knowledge about analytical methods for homocysteine thiolactone determination in biological samples, Trends Anal. Chem. – TrAC, 159 (2023) 116906.
8. R. Głowacki, J. Piechocka, E. Bald, G. Chwatko, Application of Separation Techniques in Analytics of Biologically Relevant Sulfur Compounds, in Handbook of Bioanalytics (B. Buszewski, I. Baranowska (eds.)), Springer Nature, 2022, 233-256.
9. Bekier, J. Gatkowska, M. Chyb, J. Sokołowska, G. Chwatko, R. Głowacki, A. Paneth, K. Dzitko, 4-Arylthiosemicarbazide derivatives – pharmacokinetics, toxicity and anti-Toxoplasma gondii activity in vivo, Eur. J. Med. Chem. 244 (2022) 114812.
10. J. Piechocka, M. Wieczorek, R. Głowacki, Gas Chromatography – Mass Spectrometry Based Approach For the Determination of Methionine – Related Sulfur Containing Compounds In Human Saliva, Int. J. Mol. Sci. 21, 2020, 9252.
11. J. Piechocka, M. Wrońska, R. Głowacki, Chromatographic strategies for the determination of aminothiols in human saliva, Trends Anal. Chem. – TrAC, 126 (2020) 115866.
12. J. Piechocka, M. Wrońska, G. Chwatko, H. Jakubowski, R. Głowacki, Quantification of homocysteine thiolactone in human saliva and urine by gas chromatography-mass spectrometry, J. Chromatogr. B. 1149 (2020) 122155.
13. J. Piechocka, M. Wrońska, I.E. Głowacka, R. Głowacki, 2-(3-Hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic Acid, Novel Metabolite of Pyridoxal 5’-Phosphate and Cysteine Is Present in Human Plasma - Chromatographic Investigations, Int. J. Mol. Sci. 21 (2020) 3548.
14. K. Morawska, N. Festinger, G. Chwatko, R. Głowacki, W. Ciesielski, S. Smarzewska, Rapid electroanalytical procedure for sesamol determination in real samples, Food Chem. 309 (2020) 125789.
15. P. Kubalczyk K. Purgat, P. Olejarz, I. Kośka, R. Głowacki, Determination of homocysteine thiolactone in human urine by capillary zone electrophoresis and single drop microextraction, Anal. Biochem., 596 (2020) 113640.
16. R.M. Dyson, H.K. Palliser, N. Wilding, M.A. Kelly, G. Chwatko, R. Głowacki, M.J. Berry, X. Ni, I.M.R Wright, Microvascular circulatory dysregulation driven in part by cystathionine-gamma-lyase: a new paradigm for cardiovascular compromise in the preterm newborn, Microcirculation, (2019) 26: e12507.
17. K. Borowczyk, J. Piechocka, R. Głowacki, I. Dhar, Ø. Midtun, G.S. Tell, P.M. Ueland, O. Nygård, H. Jakubowski, Urinary Excretion of Homocysteine Thiolactone and the Risk of Acute Myocardial Infarction in Coronary Artery Disease Patients; the Western Norway B-Vitamin Intervention Trial, J. Int. Med., 285 (2019) 232-244.
18. K. Purgat, K. Borowczyk, R. Zakrzewski, R. Głowacki, P. Kubalczyk, Determination of nikethamide by micellar electrokinetic chromatography, Biomed. Chromatogr. 2019;33:e4571.
19. Kamińska, I.E. Głowacka, B. Pasternak, R. Głowacki, G. Chwatko, New method for simultaneous determination of lipoyllysine and α-lipoic acid by high performance liquid chromatography, Bioanalysis, 11 (2019) 1359-1373.
20. G. Chwatko, M. Krawczyk, M. Iciek, A. Kamińska, A. Bilska-Wilkosz, B. Marcykiewicz, R. Głowacki, Determination of lipoic acid in human plasma by high-performance liquid chromatography with ultraviolet detection, Arab. J. Chem., 12 (2019) 4878–4886.
21. J. Perła-Kajan, K. Borowczyk, R. Głowacki, O. Nygård, H. Jakubowski, Paraoxonase 1 (PON1) genotype and activity affect homocysteine thiolactone levels in humans, FASEB Journal, 32 (2018) 6019-6024.
22. M. Wrońska, G. Chwatko, K. Borowczyk, J. Piechocka, P. Kubalczyk, R. Głowacki, Application of GC-MS technique for the determination of homocysteine thiolactone in human urine, J. Chromatogr. B, 1099 (2018) 18–24. P.
CONTACT DETAILS AND OFFICE HOURS
Pomorska 163/165 90-236 Łódź
e-mail: rafal.glowacki@chemia.uni.lodz.pl
Pomorska 163/165 90-236 Łódź
phone: 42-635-58-35
Pomorska 163/165 room: 113 90-236 Łódź